Yu Lan graduated from the Third Military Medical University of PLA with a bachelor's degree in clinical medicine in 1995, and received her Ph.D. in Genetics from the Academy of Military Medical Sciences in 2007. She was engaged in scientific research at the Academy of Military Medical Sciences from 2008 to 2016, and has been working as a principal investigator in Jinan University from 2017. She focuses on the lineage relationships and regulatory mechanisms of the developmental hematopoietic cells and blood vessels. In recent years, using a series of single-cell technologies and precise lineage tracing strategies, her group characterized the transcriptomic landscape of embryonic vascular and hematopoietic systems in mammals, resolved arteriovenous specification patterns in early mammalian vascular development, discovered functional heterogeneities in hemogenic endothelial cells and nascent hematopoietic stem cells, and revealed several epigenetic regulatory mechanisms, including lnc-RNA and RNA splicing, underlying the ontogeny of hematopoietic stem cells. As corresponding author (including co-corresponding), she has published research articles in Nature (2020), Nature Immunology (2022), Cell Stem Cell (2019), Immunity (2019), Developmental Cell (2011), Cell Research (2017/2019/2020/2021/2022), Science Advances (2022), Nature Communications (2022), Blood (2014/2021), and Circulation Research (2016), et al..